Thymidine in Cells
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چکیده
منابع مشابه
Fractionation of Thymidine Phosphokinase, Thymidine 5'-monophosphate Phosphokinase and Thymidine 5'-diphosphate Phosphokinase in Extracts of Landschutz Ascites-tumour Cells.
1. Extracts of Landschutz ascites-tumour cells have been fractionated by treatment with acid, alumina C(gamma) gel and Sephadex G-100 to yield purified preparations of thymidine phosphokinase, thymidine 5'-monophosphate phosphokinase and thymidine 5'-diphosphate phosphokinase. 2. These results clearly demonstrate the existence in Landschutz ascites tumour of three phosphokinases each of which c...
متن کاملControl of thymidine kinase synthesis in IHD vaccinia virus-infected thymidine kinase-deficient LM cells.
The synthesis of vaccinia virus-induced thymidine kinase is normally arrested several hours after infection. In thymidine kinase-deficient LM cells infected with IHD strain of vaccinia virus, arrest occurs whether or not viral DNA synthesis is inhibited. With virus inactivated by UV irradiation, enzyme synthesis takes place, but arrest is abolished. It is suggested that an early viral genetic f...
متن کاملIsolation of thymidine-resistant cells from a thymidine-sensitive acute lymphoblastic leukemia cell line.
Malignant cells have enhanced sensitivity to inhibition of growth by thymidine. Cell growth of the permanent lymphoid cell line CCRF-CEM, originating from a patient with acute lymphoblastic leukemia, is inhibited by 3 x 10(-5) M thymidine, compared to 1 to 5 x 10(-3) M thymidine required to inhibit growth of normal lymphoid lines. Thymidine-resistant cells were isolated at a frequency of approx...
متن کاملThymidine Degradation Products in Plant Tissues Labeled with Tritiated Thymidine
A study of the metabolic pathways of H(3)-thymidine utilization in buds of Lilium longiflorum and root tips of Vicia faba was undertaken in order to obtain information that might explain the binding of H(3) from H(3)-thymidine in the cytoplasm of these plants. H(3)-thymidine was administered for various periods of time, the tissues were fixed and processed in the manner routinely used in prepar...
متن کاملThymidine diphosphate mannose and thymidine diphosphate rhamnose in Streptomyces grieus.
Moflwain, H. (1937). J. chem. Soc. p. 1704. Mahler, H. R., Tomisek, A. & Huennekens, F. M. (1953). Exp. Cell Res. 4, 208. Margoliash, E. (1954). Biochem. J. 56, 529. Meyerhof, 0. (1933). Nature, Lond., 132, 337. Molinari, R. & Lara, F. J. S. (1960). Biochem. J. 75, 57. Nemeth, A. M., Russell, C. S. & Shemin, D. (1957). J. biol. Chem. 229, 415. Neuberg, 0. (1913). Biochem. Z. 49, 502. Nygaard, A...
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ژورنال
عنوان ژورنال: Nature
سال: 1968
ISSN: 0028-0836,1476-4687
DOI: 10.1038/217107b0